itraconazole  - Drug Details
📊 Estimates itraconazole  Dialyzability By Different_Modalities

itraconazole 

Complete Drug Information

Drug Name
itraconazole 
Trade Names
Sporanox, Sporaz, Orungal
Pregnancy Category
AU: B3
Bioavailability
~55%, maximal if taken with full meal
Routes of Administration
Oral, solution), vaginal suppository, intravenous
Protein Binding
99.80%%
Metabolism
Extensive in liver (CYP3A4)
Elimination
21 hours
Excretion
Kidney (35%), faeces (54%)
Formula
C35H38Cl2N8O4
Molar Mass
705.64
Melting Point
165 °C
Volume of Distribution
10 L/kg

🤰 Pregnancy Category Information

Category: AU: B3

Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus. Animal studies have shown evidence of an increased occurrence of fetal damage, the significance of which is considered uncertain in humans.