Prophene_65 - Drug Details
📊 Estimates Prophene_65 Dialyzability By Different_Modalities

Prophene_65

Complete Drug Information

Drug Name
Prophene_65
Trade Names
Darvon, Darvocet
Pregnancy Category
AU: C
Bioavailability
40%
Routes of Administration
Oral, intravenous, rectal
Protein Binding
78%%
Metabolism
Liver-mediated, CYP3A4-mediated N-demethylation (major), aromatic hydroxylation (minor) and ester hydrolysis (minor)
Elimination
6–12 hours; 30–36 hours (active metabolite, nordextropropoxyphene)
Excretion
Urine (major), breastmilk (minor)
Formula
C22H29NO2
Molar Mass
339.479
Melting Point
75 °C
Drug Class
Opioid
Volume of Distribution
C22H29NO2

🤰 Pregnancy Category Information

Category: AU: C

Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing harmful effects on the human fetus or neonate without causing malformations. These effects may be reversible.