palonosetron  - Drug Details
📊 Estimates palonosetron  Dialyzability By Different_Modalities

palonosetron 

Complete Drug Information

Drug Name
palonosetron 
Trade Names
Aloxi
Pregnancy Category
AU: B1
Bioavailability
97% (oral)
Routes of Administration
Intravenous,Oral
Protein Binding
62%%
Metabolism
Liver, 50% (mostly CYP2D6-mediated, CYP3A4 and CYP1A2 also involved)
Elimination
Approximately 40–50 hours
Excretion
Kidney, 80% (of which 49% unchanged); fecal (5 to 8%)
Formula
C19H24N2O
Molar Mass
296.414
Melting Point
87 to 88 °C
Volume of Distribution
6.9 L/kg

🤰 Pregnancy Category Information

Category: AU: B1

Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus. Animal studies have not shown evidence of an increased occurrence of fetal damage.