nusinersen  - Drug Details
📊 Estimates nusinersen  Dialyzability By Different_Modalities

nusinersen 

Complete Drug Information

Drug Name
nusinersen 
Trade Names
Spinraza
Pregnancy Category
AU: B1
Bioavailability
100% (intrathecal)
Routes of Administration
Intrathecal
Protein Binding
<25% (in CSF), >94% (in plasma)%
Metabolism
Exonuclease (3'- and 5')-mediated hydrolysis
Elimination
135–177 days (in CSF), 63–87 days (in plasma)
Formula
C234H323N61Na17O128P17S17
Molar Mass
7500.86
Volume of Distribution
C234H323N61Na17O128P17S17

🤰 Pregnancy Category Information

Category: AU: B1

Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus. Animal studies have not shown evidence of an increased occurrence of fetal damage.