PSF MEMBRANEShave the capacity to remove a broad range of uremic toxins, effectively retain endotoxins, and, provide intrinsic biocompatibility and low cytotoxicity.In addition to its higher sieving capability, increased hydraulic…
Solute removal in hemodialysis occurs through a combination of diffusion, convection, and adsorption.The uremic solutes removed by hemodialysis are divided into three main categoriesSmall water soluble compounds such as urea…
Membrane performance, as determined by the effectiveness of solute clearance and biocompatibility, is of greatest concern when choosing a dialyzer. Technological advances in membrane design, chemical composition, and sterilization methods…
Priming volume: Is how much blood needs to fill dialyzer capillaries, it consider as dead blood volume. it is varies among dialyzers, as a role of thumb, more priming volume,…
Symmetric Membrane fibers Symmetric membranes, which can be derived either from cellulose or entirely from synthetic polymers, have a homogeneous configuration throughout the membrane wall, with both the inner and…
As described by Daugirdas, many excellent nephrologists follow an empiric model when devising the hemodialysis prescription: place patients on the largest dialyzer that they can afford,dialyze them for the longest…
As described by Daugirdas, many excellent nephrologists follow an empiric model when devising the hemodialysis prescription: place patients on the largest dialyzer that they can afford,dialyze them for the longest…
The extent to which a drug is affected by dialysis is determined primarily by several physicochemical characteristics of the drug, which are briefly described in the text that follows.These include…
Dialyzer selection criteria There is no definite selection criteria, Choosing dialyzers with low blood volume: Low body weight, like children Hypotensive patients. First dialysis sessions Coagulation issues, like using no…
Complement Activation The level of complement activation produced by a membrane is considered a significant determinant of membrane biocompatibility. All membranes activate complement and leukocytes to some extent, but unmodified…
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