Xylocaine
Classification:
Antidysrhythmic
Indications:
• VF, VT, PVC’s
Actions:
• Sodium channel blocker
• Depresses ventricular irritability and automaticity
• Increases fibrillation threshold
Dosage:
• VF & Pulseless VT = 1.0 – 1.5mg/kg. Repeat at half dose if necessary. Max: 3mg/kg
• VT or PVC’s = 0.5 – 0.75 mg/kg up to 1 – 1.5mg/kg
• then 0.5 – 0.75mg/kg every 5 – 10 minutes IF NEEDED, not to exceed 3mg/kg
Infusion:
• Maintenance Infusion: Mix 2gm/500mL D5W (4mg/mL)
• Infuse @ 1 – 4mg/min (15 – 60 mL/hr)
Route:
• IV/IO, ET
Side effects:
• Muscle tremors, paresthesias, CNS symptoms – seizures