DESCRIPTION
A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
CATEGORIES
Anti-Inflammatory Agents, Non-Steroidal,Cyclooxygenase Inhibitors.
CHEMICAL FORMULA
C15H13N3O4S
COMPOSITION
Piroxicam 20 MG
INDICATION
For treatment of osteoarthritis and rheumatoid arthritis.
PHARMACODYNAMICS
Piroxicam is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Piroxicam works by reducing hormones that cause inflammation and pain in the body. Piroxicam is used to reduce the pain, inflammation, and stiffness caused by rheumatoid arthritis and osteoarthritis.
No Information
ABSORPTION
Well absorbed following oral administration.
VOLUME DISTRIBUTION
0.14 L/kg
METABOLISM
Renal
ELIMINATION
Piroxicam and its biotransformation products are excreted in urine and feces, with about twice as much appearing in the urine as in the feces. Approximately 5% of a piroxicam dose is excreted unchanged. However, a substantial portion of piroxicam elimination occurs by hepatic metabolism. Piroxicam is excreted into human milk.
HALF LIFE
30 to 86 hours
TOXICITY
Symptoms of overdose include drowsiness, nausea, stomach pain, and/or vomiting.
FOOD INTERACTIONS
avoid alcohol
SIDE EFFECTS
Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing. Belly pain or heartburn. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.