DESCRIPTION
Cefuroxime Axetil is a semisynthetic, broad-spectrum cephalosporin antibiotic for oral administration.
CATEGORIES
cephalosporin antibiotic.
CHEMICAL FORMULA
C20H22N4O10S
COMPOSITION
Cefuroxime axetil 250 MG
INDICATION
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefuroxime Axetil and other antibacterial drugs, Cefuroxime Axetil tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
No Information
ABSORPTION
After oral administration, Cefuroxime Axetil is absorbed from the gastrointestinal tract and rapidly hydrolyzed by nonspecific esterases in the intestinal mucosa and blood to cefuroxime.
METABOLISM
Cefuroxime is subsequently distributed throughout the extracellular fluids. The axetil moiety is metabolized to acetaldehyde and acetic acid.
ELIMINATION
Cefuroxime is excreted unchanged in the urine; in adults, approximately 50% of the administered dose is recovered in the urine within 12 hours. The pharmacokinetics of cefuroxime in the urine of pediatric patients have not been studied at this time. Until further data are available, the renal pharmacokinetic properties of Cefuroxime Axetil established in adults should not be extrapolated to pediatric patients.
FOOD INTERACTIONS
avoid alcohol
SIDE EFFECTS
Chills,Diarrhea,fever,general feeling of illness or discomfort,headache,itching of the vagina or genital area,pain during sexual intercourse,rigidity,sweating,thick, white vaginal discharge with no odor or with a mild odor.