All dialysis machine equipped with volume metric UF control.Blood flow speed is accurately calibrated.-+5%All modern artificial kidneys (Dialyzers) are semi identical.Urea clearance affect patients outcome.Dialyzer clearance depend on blood flow speed.Dialyzer clearance decreased throughout treatment time.Delivered blood flow mainly depend on blood access efficacy.Butter KT/V better patient outcome.All modern dialyzers tolerate maximum TMP above 500mmhg.All dialyzers membrane are biocompatible.