DESCRIPTION
Deflazacort is an inactive prodrug which is metabolized rapidly to the active drug 21-desacetyldeflazacort.Its potency is around 70–90% that of prednisone.
CATEGORIES
Corticosteroid Hormones , Immunosuppressants
CHEMICAL FORMULA
C25H31NO6
COMPOSITION
Deflazacort 30mg
INDICATION
This medication is a glucocorticoid, prescribed for anti-inflammatory conditions, and used as an immunosuppressant. It is a prodrug.
No Information
METABOLISM
By plasma esterases, to active metabolite
ELIMINATION
Renal (70%) and fecal (30%)
HALF LIFE
1.1–1.9 hours (metabolite)
FOOD INTERACTIONS
avoid alcohol
SIDE EFFECTS
GI disturbances, musculoskeletal, endocrine, neuropsychiatric, ophthalmic, fluid and electrolyte disturbances; susceptible to infection, impaired healing, hypersensitivity, skin atrophy, striae, telangiectasia, acne, myocardial rupture following recent MI, thromboembolism.