Levophed
Classification:
Adrenergic stimulator (sympathetic nervous system). Vasopressor
Indications:
• Hypotension refractory to Dopamine
• SBP < 70 mmHg and low peripheral resistance
Actions:
• Primarily alpha effects causing an increase in systemic vascular resistance through vasoconstriction
Dosage:
• Mix 4mg/250ml D5W or NS = 16mcg/mL
• Begin infusion at 0.1-0.5mcg/kg/min (8-40mg=30-150mL/hr)
Route:
• IV infusion only
Side Effects:
• Increased myocardial work and oxygen consumption. May cause tachycardia and
myocardial ischemia. Severe tissue necrosis if infiltrated
