Classification:
Adrenergic (sympathetic) stimulator
Indications:
• Cardiac arrest *Give early in non-shockable rhythms. (Q4 min fits into CPR sequence)
• Symptomatic bradycardia refractory to Atropine & transcutaneous pacing (drip only)
• Severe hypotension where fluids are contraindicated or unsuccessful
Actions:
• Positive effects, including increased heart rate, contractility, and automaticity
• Positive effects, including peripheral vasoconstriction.
Dosage:
• Bolus: 1mg IV repeat at 3 – 5 minute intervals
Infusion:
• 4mg/250mL’s (16 mcg/mL) D5W or NS.
• For Bradycardia: Infuse 2 -10mcg/min (14-70 mL/hr); titrate to HR greater than 60
• For Hypotension 2-10mcg/min; titrate to SBP above 90 or MAP above 65 mmHg
Route:
• IV/IO, ET, IV infusion
Side effects:
• Tachycardia, hypertension, increased O2 demand, PVC’s, tachyarrhythmias
