Indications
used as a sclerosant in the treatment of varicose veins and oesophageal varices.
Adverse effect
Monoethanolamine oleate is irritant to skin and mucous membranes. Local injection may cause sloughing, ulceration,
and, in severe cases, necrosis. Pain may occur at the site of injection. Patients receiving treatment for oesophageal varices may develop pleural effusion or infiltration. Hypersensitivity reactions have been reported. Sclerotherapy should not be used to treat varicose veins of the legs in patients with thrombosis or a tendency to thrombosis, or with acute phlebitis, marked arterial, cardiac, or renal disease, local or systemic infections, or uncontrolled metabolic disorders such as diabetes mellitus.Effects on the kidneys: Acute renal failure, which clears spontaneously within 3 weeks
Dosage
sclerotherapy of varicose veins
2 to 5 mL of a 5% solution of monoethanolamine oleate is injected slowly into empty isolated sections of vein, divided between 3 or 4 sites. Injection into full veins is also possible. sclerotherapy of oesophageal varices 1.5 to 5 mL of a 5% solution per varix to a maximum total dose of 20 mL per treatment session. Treatment may be given in the initial management of bleeding varices, then repeated at intervals until the varices are occluded.
Products
ETHANOLAMINE OLEATE AMPS 5 % 5 ML