DESCRIPTION
Camphor -A bicyclic monoterpene ketone found widely in plants, especially cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. Chlorothymol-an antibacterial for topical use. Eucalyptol -Eucalyptol is a natural organic compound which is a colorless liquid. It is a cyclic ether and a monoterpenoid. Eucalyptol is an ingredient in many brands of mouthwash and cough suppressant. It controls airway mucus hypersecretion and asthma via anti-inflammatory cytokine inhibition. Eucalyptol is an effective treatment for nonpurulent rhinosinusitis. Eucalyptol reduces inflammation and pain when applied topically. It kills leukaemia cells in vitro. Menthol-Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. It is a waxy, crystalline substance, clear or white in color, which is solid at room temperature and melts slightly above. The main form of menthol occurring in nature is (-)-menthol, which is assigned the (1R,2S,5R) configuration. Menthol has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation.
CATEGORIES
Eucalyptol – Anti-Infective Agents,Solvents.Menthol-Antipruritics.
CHEMICAL FORMULA
Camphor -C10H16O.Chlorothymol-C10H13OC1.Eucalyptol -C10H18O. Menthol-C10H20O.
COMPOSITION
Camphor 25 mg + Chlorothymol 5 mg+ Eucalyptol 125 mg+Menthol 55 mg+ Terpinol 120 mg
INDICATION
Menthol-Used to treat occasional minor irritation, pain, sore mouth, and sore throat as well as cough associated with a cold or inhaled irritants.
PHARMACODYNAMICS
Menthol-Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Menthol’s ability to chemically trigger cold-sensitive receptors in the skin is responsible for the well known cooling sensation that it provokes when inhalated, eaten, or applied to the skin. It should be noted that menthol does not cause an actual drop in temperature.
No Information
TOXICITY
Eucalyptol -Oral, rat LD50: 2480 mg/kg .Menthol-Menthol, DL: ORAL (LD50): Acute: 2900 mg/kg [Rat], 3100 mg/kg [Mouse]. DERMAL (LD50): Acute: 5001 mg/kg [Rabbit].