CASTOR OIL
aborashyd83 The fatty oil obtained by cold expression from the seeds of Ricinus communis. It is a clear, almost colourless or slightly yellow, viscous, hygroscopic liquid. Miscible with alcohol and with…
2022
BISACODYL
Mode of actionAct by direct stimulation of nerve endings in colonic mucosa to increase intestinal motility. May cause accumulation of water and electrolytes in the colonic lumen. IndicationsConstipation; Bowel preparation…
BUDESONIDE
Mode of actionAnti-inflammatory. Formulation delivers budesonide predominantly to the ileum and ascending colon. Systemic absorption is reduced by high first-pass metabolism, producing mainly local effects in the gut. However, some…
SULFASALAZINE
Mode of actionExact mechanism unknown but exert local anti-inflammatory action in the bowel wall.IndicationsUlcerative colitis; acute and remission maintenance; rheumatoid arthritis; Crohn’s disease (limited role in colonicdisease; much less effective…
MESALAZINE
Mode of actionExact mechanism unknown but exert local anti-inflammatory action in the bowel wall.IndicationsInflammatory large bowel disease, acute and maintenance; Ulcerative colitis, rectal Ulcerative colitis, rectal(suppository) and rectosigmoidal (enema) disease.ContraindicationsAllergy…
LOPERAMIDE
Mode of actionActivate opioid receptors in the gut wall, decreasing bowel motility and increasing fluid absorption.IndicationsDiarrhoea, usually short term treatment in adults, Intestinal stoma (to reduce frequency and fluidity of…
TERLIPRESSIN
Mode of actionVasoconstrictor.IndicationsBleeding oesophageal varices; Hepatorenal syndrome.Specific considerationsHypertension, atherosclerosis, cardiac disease: caution required due to vasoconstriction and fluid retention caused byterlipressin.Pregnancy: contraindicated; may stimulate uterine contraction.Breastfeeding: safe to use.Adverse effectsabdominal…
SOMATOSTATIN
Mode of actionInhibit release of growth hormone and of various peptides of the gastroenteropancreatic endocrine system.IndicationsMarketed: Acromegaly where surgery or radiotherapy are contraindicated or have failed to control disease, or…
PANTOPRAZOLE
Mode of actionIrreversibly inactivate the hydrogen/potassium ATPase enzyme system (proton pump), suppressing both stimulatedand basal acid secretion. When PPIs are stopped, acid secretion is restored by synthesis of new hydrogen/potassiumATPase.…
OMEPRAZOLE
Mode of actionIrreversibly inactivate the hydrogen/potassium ATPase enzyme system (proton pump), suppressing both stimulatedand basal acid secretion. When PPIs are stopped, acid secretion is restored by synthesis of new hydrogen/potassiumATPase.IndicationsMarketed:…