2022

URSODEOXYCHOLIC ACID Mode of actionUnclear; alters bile acid composition resulting in greater concentration of ursodeoxycholic acid; increases bile acidoutput and bile flow. Some evidence for immunological mechanisms.IndicationsChronic cholestatic liver diseases…

MACROGOL

Mode of actionso-osmotic solutions containing electrolytes and polyethylene glycol (PEG), which clean the bowel by causing diarrhoea.IndicationsUsed before colonic surgery, colonoscopy, or radiological examination to ensure the bowel is free…

MACROGOL

Mode of actionso-osmotic solutions containing electrolytes and polyethylene glycol (PEG), which clean the bowel by causing diarrhoea. IndicationsUsed before colonic surgery, colonoscopy, or radiological xamination to ensure the bowel is…

PHOSPHATE ENEMA

Mode of action Non-absorbable salts retain fluid in the colon by osmotic effect and stimulate peristalsis. IndicationsBowel preparation, for GI endoscopic or surgical procedures; Chronic constipation. ContraindicationsIntestinal obstruction, partial or…

LACTULOSE

Mode of actionPoorly absorbed, metabolized by colonic bacteria; it exerts an osmotic effect in the colon. Increase in intraluminal pressure stimulates peristalsis.Beneficial effects in hepatic encephalopathy are thought to result…

SENNA

Mode of actionAct by direct stimulation of nerve endings in colonic mucosa to increase intestinal motility. May cause accumulation of water and electrolytes in the colonic lumen.IndicationsConstipation.ContraindicationsIntestinal obstruction, partial or…