gentamicin  - Removal Estimates

💊 gentamicin 

gentamicin  Dialyzability By Different Modalities

MW: 477.603
Protein Binding: 0–10%%
Vd: 0.3 L/kg

📊 Removal Estimates

Estimates based on drug properties and standard treatment parameters.

🩸

Hemodialysis

135.0 mL/min
Highly Dialyzable
Significant removal expected. Half-life: 2 h. Consider post-dialysis supplementation.
Data Used:
✅ molar_mass, mw_factor, vd, vd_factor, half_life
⚠️ Missing: protein_binding
Free fraction: 0.5 Mw factor: 1 Vd factor: 1 Hl factor: 1 Half life: 2 h Half life category: Short (1-4h)
🫀

Peritoneal Dialysis

2.4 mL/min
Low PD Clearance
Minimal removal expected. No supplementation needed. Half-life: 2 h.
Data Used:
✅ molar_mass, half_life
⚠️ Missing: protein_binding
Free fraction: 0.5 Half life: 2 h Half life category: Short (1-4h)
🔄

Plasmapheresis (TPE)

Unable to Assess
Insufficient data for TPE risk assessment. Protein binding and Vd required.
Data Used:
✅ vd, half_life
⚠️ Missing: protein_binding
Half life: 2 h Half life category: Short (1-4h)
🧪

Hemoadsorption

Moderate Effectiveness
Some removal possible. May be useful in overdose.
Data Used:
✅ vd, half_life
Half life: 2 h Half life category: Short (1-4h)

📋 Summary of Estimates

Modality Clearance/Value Half-Life Classification Data Quality
Hemodialysis 135.0 mL/min 2 h Highly Dialyzable Partial Data
Peritoneal Dialysis 2.4 mL/min 2 h Low PD Clearance Partial Data
Plasmapheresis (TPE) Unable to Assess 2 h N/A Partial Data
Hemoadsorption Moderate Effectiveness 2 h N/A Complete Data

📌 Important Notes

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