Estimates based on drug properties and standard treatment parameters.
29.8 mL/min
Poorly Dialyzable
Minimal removal expected. Half-life: 12 hours (fosinoprilat). No supplementation needed.
Data Used:
✅
protein_binding, molar_mass, mw_factor, vd, vd_factor, half_life
Free fraction:
0.13
Mw factor:
0.85
Vd factor:
1
Hl factor:
1
Half life:
12 hours (fosinoprilat)
Half life category:
Long (12-24h)
1.1 mL/min
Low PD Clearance
Minimal removal expected. No supplementation needed. Half-life: 12 hours (fosinoprilat).
Data Used:
✅
protein_binding, molar_mass, half_life
Free fraction:
0.13
Half life:
12 hours (fosinoprilat)
Half life category:
Long (12-24h)
High Risk
High protein binding and small Vd. Monitor levels and consider supplementation.
Data Used:
✅
protein_binding, vd, half_life
Half life:
12 hours (fosinoprilat)
Half life category:
Long (12-24h)
High Effectiveness
Excellent candidate for hemoperfusion. Effective in overdose situations. Rebound expected.
Data Used:
✅
vd, half_life
Half life:
12 hours (fosinoprilat)
Half life category:
Long (12-24h)
