Estimates based on drug properties and standard treatment parameters.
27.5 mL/min
Poorly Dialyzable
Minimal removal expected. Half-life: 155 hours (mean: 85 hours). No supplementation needed. Despite long half-life, clearance is low due to other factors.
Data Used:
✅
molar_mass, mw_factor, vd, vd_factor, half_life
⚠️ Missing:
protein_binding
Free fraction:
0.5
Mw factor:
0.85
Vd factor:
0.2
Hl factor:
1.2
Half life:
155 hours (mean: 85 hours)
Half life category:
Extended (> 72h)
2.0 mL/min
Low PD Clearance
Minimal removal expected. No supplementation needed. Half-life: 155 hours (mean: 85 hours).
Data Used:
✅
molar_mass, half_life
⚠️ Missing:
protein_binding
Free fraction:
0.5
Half life:
155 hours (mean: 85 hours)
Half life category:
Extended (> 72h)
Unable to Assess
Insufficient data for TPE risk assessment. Protein binding and Vd required.
Data Used:
✅
vd, half_life
⚠️ Missing:
protein_binding
Half life:
155 hours (mean: 85 hours)
Half life category:
Extended (> 72h)
Low Effectiveness
Poor candidate for hemoperfusion. Drug is distributed in tissues. Despite long half-life, large Vd prevents significant removal.
Data Used:
✅
vd, half_life
Half life:
155 hours (mean: 85 hours)
Half life category:
Extended (> 72h)
