Estimates based on drug properties and standard treatment parameters.
187.9 mL/min
Highly Dialyzable
Significant removal expected. Half-life: 3.6 hours (aciclovir). Consider post-dialysis supplementation.
Data Used:
✅
protein_binding, molar_mass, mw_factor, vd, vd_factor, half_life
Free fraction:
0.87
Mw factor:
1
Vd factor:
0.8
Hl factor:
1
Half life:
3.6 hours (aciclovir)
Half life category:
Short (1-4h)
3.9 mL/min
Low PD Clearance
Minimal removal expected. No supplementation needed. Half-life: 3.6 hours (aciclovir).
Data Used:
✅
protein_binding, molar_mass, half_life
Free fraction:
0.87
Half life:
3.6 hours (aciclovir)
Half life category:
Short (1-4h)
Low Risk
This drug is unlikely to be significantly removed by TPE.
Data Used:
✅
protein_binding, vd, half_life
Half life:
3.6 hours (aciclovir)
Half life category:
Short (1-4h)
Moderate Effectiveness
Some removal possible. May be useful in overdose.
Data Used:
✅
vd, half_life
Half life:
3.6 hours (aciclovir)
Half life category:
Short (1-4h)
