iloprost  - Removal Estimates

💊 iloprost 

iloprost  Dialyzability By Different Modalities

MW: 360.494
Protein Binding: 60%%
Vd: 0.6 L/kg

📊 Removal Estimates

Estimates based on drug properties and standard treatment parameters.

🩸

Hemodialysis

69.1 mL/min
Moderately Dialyzable
Some removal expected. Half-life: 30 minutes. Monitor drug levels. Short half-life suggests rapid endogenous clearance may minimize impact of HD.
Data Used:
✅ protein_binding, molar_mass, mw_factor, vd, vd_factor, half_life
Free fraction: 0.4 Mw factor: 1 Vd factor: 0.8 Hl factor: 0.8 Half life: 30 minutes Half life category: Ultra-short (< 1h)
🫀

Peritoneal Dialysis

2.5 mL/min
Low PD Clearance
Minimal removal expected. No supplementation needed. Half-life: 30 minutes.
Data Used:
✅ protein_binding, molar_mass, half_life
Free fraction: 0.4 Half life: 30 minutes Half life category: Ultra-short (< 1h)
🔄

Plasmapheresis (TPE)

Low Risk
This drug is unlikely to be significantly removed by TPE.
Data Used:
✅ protein_binding, vd, half_life
Half life: 30 minutes Half life category: Ultra-short (< 1h)
🧪

Hemoadsorption

Moderate Effectiveness
Some removal possible. May be useful in overdose.
Data Used:
✅ vd, half_life
Half life: 30 minutes Half life category: Ultra-short (< 1h)

📋 Summary of Estimates

Modality Clearance/Value Half-Life Classification Data Quality
Hemodialysis 69.1 mL/min 30 minutes Moderately Dialyzable Complete Data
Peritoneal Dialysis 2.5 mL/min 30 minutes Low PD Clearance Complete Data
Plasmapheresis (TPE) Low Risk 30 minutes N/A Complete Data
Hemoadsorption Moderate Effectiveness 30 minutes N/A Complete Data

📌 Important Notes

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