statins and ESRD Dialysis statins and ESRD in spite of strong evidence of their role in decreasing morbidity and mortality of CVD and their role in slow progression of chronic kidney disease, they have no benefit in ESRD on dialysis patients. in dialysis patients, still CVD remain the main cause of morbidity and mortality due to calcium phosphorous abnormalities leads to vascular calcification. the statins side effect may worsen their complains