📄 Function of Proximal tubule
Many solutes are reabsorbed in the early portions of the proximal tubule:
85% of filtered sodium bicarbonate
40% of sodium chloride
60% of water is reabsorbed in direct proportion to salt osmatic pressure
nearly all of filtered organic solutes, including glucose and amino acids glucose, amino acids, and other organic solutes are reabsorbed by specific transport systems
Sodium bicarbonate reabsorbed in the proximal tubule depends on the action of sodium/hydrogen exchanger which is found in the luminal membrane of the proximal tubule epithelial cell.
Inhibition of carbonic anhydrase decreases bicarbonate reabsorption in proximal
