INDICATIONS: Podocon-25 ® (25% podophyllin in benzoin tincture) is indicated for the removal of soft genital (venereal) warts (condylomata acuminata) (4) .

WARNINGS: Podophyllin is a powerful caustic and severe irritant.

Keep away from the eyes; if eye contact occurs, flush with copious amounts of warm water and consult physician or poison control center immediately for advice.

ADVERSE REACTIONS: The use of topical podophyllin has been known to result in paresthesia, polyneuritis, paralytic ileus, pyrexia, leukopenia, thrombocytopenia, coma and death (5) .

Pregnancy: There have been reports of complications associated with the topical use of podophyllin on condylomata of pregnant patients including birth defects, fetal death and stillbirth (6) .

In the absence of controlled safety studies, podophyllin remains contraindicated for use on pregnant patients.

Nursing Mothers: It is not known whether podophyllin is excreted in human milk following topical application.

In the absence of controlled safety studies, podophyllin remains contraindicated for use on nursing patients.