{"id":3801,"date":"2025-03-31T18:11:50","date_gmt":"2025-03-31T18:11:50","guid":{"rendered":"https:\/\/kidneydiseaseclinic.net\/kdc\/calcium-gluconate-txt\/"},"modified":"2025-03-31T18:11:50","modified_gmt":"2025-03-31T18:11:50","slug":"calcium-gluconate-txt","status":"publish","type":"post","link":"https:\/\/kidneydiseaseclinic.net\/kdc\/calcium-gluconate-txt\/","title":{"rendered":"Calcium gluconate.txt"},"content":{"rendered":"

Calcium gluconate<\/h1>\n

CLINICAL USE <\/H3>
\nHypocalcaemia

DOSE IN NORMAL RENAL FUNCTION <\/H3>Depending on indication<\/p>\n
  • Acute hypocalcaemia:
  • 10 to 20 &nbsp &nbsp : mL calcium gluconate 10% (2.25\u20134.5 mmol calcium) slow\n
  • IV injection over 3\u201310 minutes\n
  • Oral: Dose varies depending on requirements

    PHARMACOKINETICS <\/H3>
  • Molecular weight &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp :448.4<\/li>\n
  • %Protein binding &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp :\u2013<\/li>\n
  • %Excreted unchanged in urine &nbsp &nbsp : \u2013<\/li>\n

  • Volume of distribution (L\/kg) &nbsp &nbsp &nbsp :\u2013<\/li>\n

  • half-life \u2013 normal\/ESRD (hrs)&nbsp &nbsp &nbsp :\u2013

    DOSE IN RENAL IMPAIRMENT <\/H3>

    GFR (mL\/MIN)<\/H4>
  • 20 to 50 &nbsp &nbsp : Dose as in normal renal function. Titrate to response
  • 10 to 20 &nbsp &nbsp : Dose as in normal renal function. Titrate to response
  • <10 &nbsp &nbsp &nbsp &nbsp &nbsp : Dose as in normal renal function. Titrate to response

    DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES <\/H3>
  • CAPD &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp:Dialysed. Dose as in normal renal function<\/p>\n
  • HD &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp &nbsp :Dialysed. Dose as in normal renal function
  • HDF\/high flux &nbsp :Dialysed. Dose as in normal renal function
  • CAV\/VVHD &nbsp &nbsp &nbsp:Dialysed. Dose as in normal renal function

    IMPORTANT DRUG INTERACTIONS <\/H3>Potentially hazardous interactions with other drugs\n
  • Can impair absorption of some drugs, e.g. iron, ciprofloxacin

    ADMINISTRATION <\/H3>

    Reconstition<\/H4> \u2013

    Route <\/H4>Oral, IV, IM

    Rate of Administration <\/H4>IV: slow 3\u20134 minutes for each 10 mL (2.25 mmol calcium); not greater than 20 mmol\/hour for continuous infusions

    Comments<\/H4>IV: Can be used undiluted for continuous and intermittent infusions
    \n

    OTHER INFORMATION <\/H4><\/p>\n
  • Check patient\u2019s magnesium levels\n
  • Monitor calcium and PO 4 serum levels\n
  • Calcium-Sandoz 400: 10 mmol calcium per tablet\n
  • Calcium-Sandoz 1000: 25 mmol calcium per tablet\n
  • Calcium levels cannot be corrected until magnesium levels are normal
    \n","protected":false},"excerpt":{"rendered":"

    Calcium gluconate CLINICAL USE Hypocalcaemia DOSE IN NORMAL RENAL FUNCTION<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[7],"class_list":["post-3801","post","type-post","status-publish","format-standard","hentry","category-blog","tag-post-by-auto-php"],"_links":{"self":[{"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/posts\/3801","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/comments?post=3801"}],"version-history":[{"count":0,"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/posts\/3801\/revisions"}],"wp:attachment":[{"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/media?parent=3801"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/categories?post=3801"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/tags?post=3801"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}