{"id":1624,"date":"2023-06-25T17:28:42","date_gmt":"2023-06-25T17:28:42","guid":{"rendered":"https:\/\/kidneydiseaseclinic.net\/kdc\/aluminium-hydroxide\/"},"modified":"2023-06-25T19:59:12","modified_gmt":"2023-06-25T19:59:12","slug":"aluminium-hydroxide","status":"publish","type":"post","link":"https:\/\/kidneydiseaseclinic.net\/kdc\/aluminium-hydroxide\/","title":{"rendered":"Aluminium hydroxide"},"content":{"rendered":"

<\/p>\n

Aluminium hydroxide<\/h1>\n

CLINICAL USE<\/h3>\n
  • Phosphate binding agent<\/li>\n
  • Antacid
    \n

    DOSE IN NORMAL RENAL FUNCTION<\/h3>\n<\/li>\n
  • Phosphate binder: 4\u201320 capsules daily individed doses<\/li>\n
  • Antacid: 1 capsule 4 times daily and atbedtime
    \n

    PHARMACOKINETICS<\/h3>\n<\/li>\n
  • Molecular weight                           :
    \n78<\/li>\n
  • %Protein binding                           :
    \n70\u201390<\/li>\n
  • %Excreted unchanged in urine     :
    \nNo data<\/li>\n
  • Volume of distribution (L\/kg)       :
    \nNo data<\/li>\n
  • half-life \u2013 normal\/ESRD (hrs)      :
    \nNo data<\/p>\n

    DOSE IN RENAL IMPAIRMENT<\/h3>\n

    GFR (mL\/MIN)<\/h4>\n<\/li>\n
  • 20 to 50     : Dose as in normal renal function<\/li>\n
  • 10 to 20     : Dose as in normal renal function<\/li>\n
  • <10           :
    \nDose as in normal renal function<\/p>\n

    DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES<\/h3>\n<\/li>\n
  • CAPD                :
    \nUnknown dialysability. Dose as in
    \nnormal renal function<\/li>\n
  • HD                     :
    \nUnknown dialysability. Dose as in
    \nnormal renal function<\/li>\n
  • HDF\/high flux   :
    \nUnknown dialysability. Dose as in
    \nnormal renal function<\/li>\n
  • CAV\/VVHD      :
    \nUnknown dialysability. Dose as in
    \nnormal renal function<\/p>\n

    IMPORTANT DRUG INTERACTIONS<\/h3>\n

    Potentially hazardous interactions with other drugs
    \nNone known<\/p>\n

    ADMINISTRATION<\/h3>\n

    Reconstition<\/h4>\n

    \u2013<\/p>\n

    Route<\/h4>\n

    Oral<\/p>\n

    Rate of Administration<\/h4>\n

    \u2013<\/p>\n

    Comments<\/h4>\n

    \u2013<\/p>\n

    OTHER INFORMATION<\/h4>\n<\/li>\n
  • K\/DOQI guidelines caution that CKD 5patients on chronic therapy may develop
    \naluminium toxicity; therefore best avoided
    \nin all but short-term therapy (calcium
    \ncarbonate, calcium acetate, lanthanum or
    \nsevelamer are used in chronic therapy)<\/li>\n
  • Take\/administer with or immediatelybefore meals<\/li>\n
  • In patients undergoing chronic therapywith aluminium hydroxide, serum
    \naluminium levels should be monitored<\/li>\n","protected":false},"excerpt":{"rendered":"

    Aluminium hydroxide CLINICAL USE Phosphate binding agent Antacid DOSE IN<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[7],"class_list":["post-1624","post","type-post","status-publish","format-standard","hentry","category-blog","tag-post-by-auto-php"],"_links":{"self":[{"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/posts\/1624","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/comments?post=1624"}],"version-history":[{"count":1,"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/posts\/1624\/revisions"}],"predecessor-version":[{"id":2941,"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/posts\/1624\/revisions\/2941"}],"wp:attachment":[{"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/media?parent=1624"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/categories?post=1624"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/kdc\/wp-json\/wp\/v2\/tags?post=1624"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}