<10           : 100% on alternate days
DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES
CAPD                :Unlikely to be dialysed. Dose as in GFR <10 mL/min
HD                     :Unlikely to be dialysed. Dose as in GFR <10 mL/min
HDF/high flux   :Unknown dialysability. Dose as in GFR <10 mL/min
CAV/VVHD      :Unknown dialysability. Dose as in GFR 10 to 20 mL/min
IMPORTANT DRUG INTERACTIONS
Potentially hazardous interactions with other drugs
None known
ADMINISTRATION
Reconstition
–
Route
Oral, topical
Rate of Administration
–
Comments
–
OTHER INFORMATION
Terbinafine is hepatically metabolised to two major metabolites, 80% of which are renally excretedLittle information is available regarding the handling of terbinafine in renal failure but clearance is reduced by 50% if GFR<50 mL/min In CKD 5 use with caution and monitor for side effects .