rabeprazole sodium.txt CLINICAL USE Gastric acid suppression DOSE IN NORMAL RENAL FUNCTION 10–120 mg daily, doses >100 mg in 2 divided doses PHARMACOKINETICS Molecular weight                           :381.4 %Protein binding                           :97 %Excreted unchanged in urine     : 0 (90 as metabolites) Volume of distribution (L/kg)       :0.34 half-life – normal/ESRD (hrs)      :0.7–1.5/Unchanged DOSE IN RENAL IMPAIRMENT GFR (mL/MIN) 20 to 50     : Dose as in normal renal function 10 to 20     : Dose as in normal renal function <10           : Dose as in normal renal function DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES CAPD                :Unlikely to be dialysed. Dose as in normal renal function HD                     :Not dialysed. Dose as in normal renal functionHDF/high flux   :Unlikely to be dialysed. Dose as in normal renal functionCAV/VVHD      :Unlikely to be dialysed. Dose as in normal renal function IMPORTANT DRUG INTERACTIONS Potentially hazardous interactions with other drugs Antifungals: absorption of itraconazole and ketoconazole reduced ADMINISTRATION Reconstition– Route Oral Rate of Administration –Comments– OTHER INFORMATION Interstitial nephritis has been reported with rabeprazole sodium. Tags: post-by-auto-php Continue Reading Previous Previous post: primidone.txtNext Next post: risedronate sodium.txt Related News sotalol hydrochloride.txt tazocin.txt