<10           : According to response
DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES
CAPD                :Dialysed. Dose according to response
HD                     :Dialysed. Dose according to response
HDF/high flux   :Dialysed. Dose according to response
CAV/VVHD      :Dialysed. Dose according to response
IMPORTANT DRUG INTERACTIONS
Potentially hazardous interactions with other drugsACE inhibitors and angiotensin- II antagonists: increased risk of hyperkalaemia
Ciclosporin: increased risk of hyperkalaemiaPotassium-sparing diuretics: increased risk of hyperkalaemia
Tacrolimus: increased risk of hyperkalaemia
ADMINISTRATION
Reconstition
–
Route
Oral, IV
Rate of Administration
Infusion up to 20 mmol potassium per hour except in extreme hypokalaemic emergency where some units give up to 40 mmol/hour with cardiac monitoring
Comments
Give IV solution well diluted (not exceeding 40 mmol/500 mL) for peripheral administrationMix IV solutions thoroughly to avoid layering effectSome units give more concentrated solution centrally: 100–200 mmol/100 mL sodium chloride 0.9% or glucose 5%, but at a rate not more than 20 mmol/hourCardiac monitoring mandatory
OTHER INFORMATION
Potassium chloride injection MUST NOT be injected undilutedMonitor serum potassium levels Sando K: 12 mmol potassium per tablet Slow K: 8 mmol potassium per tablet Kay-Cee-L Syrup: 1 mmol potassium per mLPotassium chloride strong 15% injection: 20 mmol potassium /10 mL