Lenograstim
CLINICAL USE
Recombinant human granulocyte-colony stimulating factor (rHuG-CSF):Reduction of duration of neutropenia
DOSE IN NORMAL RENAL FUNCTION
Cytotoxic neutropenia: 150 mcg/m 2 (19.2 MIU/m2) daily SCMobilisation of peripheral blood progenitor cells: 10 mcg/kg (1.28 MIU/kg) dailyBone marrow transplant: 150 mcg/m 2 (19.2 MIU/m2) daily as an
IV infusion
PHARMACOKINETICS
DOSE IN RENAL IMPAIRMENT
GFR (mL/MIN)
DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES
IMPORTANT DRUG INTERACTIONS
Potentially hazardous interactions with other drugs
ADMINISTRATION
Reconstition
Water for injection (1 mL)
Route
SC, IV
Rate of Administration
30 minutes
Comments
Dilute lenograstim-13.4 in up to 50 mL sodium chloride 0.9%Dilute lenograstim-33.6 in up to 100 mL sodium chloride 0.9%.