Jaundice is yellow discoloration of the whites of the eyes and skin, and is the chief sign of many disorders of the liver and biliary system. It is caused by the build-up of a substance called bilirubin, which is produced when red blood cells die. It is broken down by the liver and excreted in bile, which normally eventually passes out of the body in the urine and feces.
In hemolytic jaundice, too many red blood cells are broken down, leading to excessive amounts of bilirubin. In obstructive jaundice, a blockage prevents bilirubin from leaving the liver.
In hepatic jaundice, the liver cannot break down and excrete bilirubin normally.
Jaundice requires medical investigation, because the underlying cause may be seriou