isradipine
CLINICAL USE
Calcium-channel blocker:Essential hypertension
DOSE IN NORMAL RENAL FUNCTION
Initially 2.5 mg twice daily, increased if necessary to 10 mg twice daily
PHARMACOKINETICS
DOSE IN RENAL IMPAIRMENT
GFR (mL/MIN)
DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES
IMPORTANT DRUG INTERACTIONS
Potentially hazardous interactions with other drugs
ADMINISTRATION
Reconstition
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Route
Oral
Rate of Administration
–
Comments
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OTHER INFORMATION
In elderly patients, or where hepatic or renal function is impaired, initial dose should be 1.25 mg twice daily. Dose should be increased according to the requirements of the individual patient.