Galantamine.txt Galantamine CLINICAL USE Mild to moderate dementia in Alzheimer’s disease DOSE IN NORMAL RENAL FUNCTION 4–12 mg twice daily PHARMACOKINETICS Molecular weight                           :368.3 (as hydrobromide) %Protein binding                           :18 %Excreted unchanged in urine     : 18–22 Volume of distribution (L/kg)       :175 litres half-life – normal/ESRD (hrs)      :7–8 (XL: 8–10)/Increased DOSE IN RENAL IMPAIRMENT GFR (mL/MIN) 20 to 50     : Dose as in normal renal function 10 to 20     : Dose as in normal renal function <10           : Dose as in normal renal function but start with lower doses DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES CAPD                :Dialysed. Dose as in GFR <10           : mL/min HD                     :Dialysed. Dose as in GFR <10           : mL/minHDF/high flux   :Dialysed. Dose as in GFR <10           : mL/minCAV/VVHD      :Dialysed. Dose as in normal renal function IMPORTANT DRUG INTERACTIONS Potentially hazardous interactions with other drugs Antibacterials: erythromycin increases plasma concentration of galantamine ADMINISTRATION Reconstition– Route Oral Rate of Administration –Comments– Tags: post-by-auto-php Continue Reading Previous Previous post: GEOGRAPHIC TONGUE.txtNext Next post: HEMORRHOIDS.txt Related News sotalol hydrochloride.txt tazocin.txt