Many solutes are reabsorbed in the early portions of the proximal tubule:85% of filtered sodium bicarbonate40% of sodium chloride60% of water is reabsorbed in direct proportion to salt osmatic pressurenearly all of filtered organic solutes, including glucose and amino acids glucose, amino acids, and other organic solutes are reabsorbed by specific transport systemsSodium bicarbonate reabsorbed in the proximal tubule depends on the action of sodium/hydrogen exchanger which is found in the luminal membrane of the proximal tubule epithelial cell.Inhibition of carbonic anhydrase decreases bicarbonate reabsorption in proximal