The need of antihyperglycemic agent is decreased as the renal impairment get worse

Oral hyperglycemic agent should be avoided in esrd patientsInsulin requirement is reduced 25% at GFR 10-50 ml/minInsulin requirement is reduced 50% at GFR <10 ml/mintarget HbA1c 7.5- 8target fasting blood sugar 100 to 140mg/dl