potassium chloride

DOSE IN RENAL IMPAIRMENT

GFR (mL/MIN)

DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES

IMPORTANT DRUG INTERACTIONS

Potentially hazardous interactions with other drugsACE inhibitors and angiotensin- II antagonists: increased risk of hyperkalaemia

ADMINISTRATION

Reconstition

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Route

Oral, IV

Rate of Administration

Infusion up to 20 mmol potassium per hour except in extreme hypokalaemic emergency where some units give up to 40 mmol/hour with cardiac monitoring

Comments

Give IV solution well diluted (not exceeding 40 mmol/500 mL) for peripheral administrationMix IV solutions thoroughly to avoid layering effectSome units give more concentrated solution centrally: 100–200 mmol/100 mL sodium chloride 0.9% or glucose 5%, but at a rate not more than 20 mmol/hourCardiac monitoring mandatory

OTHER INFORMATION

Potassium chloride injection MUST NOT be injected undilutedMonitor serum potassium levels Sando K: 12 mmol potassium per tablet Slow K: 8 mmol potassium per tablet Kay-Cee-L Syrup: 1 mmol potassium per mLPotassium chloride strong 15% injection: 20 mmol potassium /10 mL