Klean-Prep
CLINICAL USE
Colonic lavage prior to diagnostic examination or surgical procedures requiring a clean colon
DOSE IN NORMAL RENAL FUNCTION
4 sachets, each reconstituted in 1 litre of water, at a rate of 250 mL every 10–15 minutes
PHARMACOKINETICS
DOSE IN RENAL IMPAIRMENT
GFR (mL/MIN)
DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES
IMPORTANT DRUG INTERACTIONS
Potentially hazardous interactions with other drugs
ADMINISTRATION
Reconstition
Each sachet in 1 litre of water
Route
Oral
Rate of Administration
250 mL every 15–30 minutes If given via NG tube, rate is 20–30 mL/ minute
Comments
Klean-Prep is formulated to be hyper- osmotic and draw water into the bowel. None is absorbed systemically
OTHER INFORMATION
Each sachet of Klean-Prep contains:Polyethylene glycol 3350 – 59.0 g —Anhydrous sodium sulphate – 5.685 g —Sodium bicarbonate – 1.685 g —Sodium chloride – 1.465 g —Potassium chloride – 0.7425 g —The electrolyte content of 1 sachet when made up in 1 litre of water is:Sodium – 125 mmol —Sulphate – 40 mmol —Chloride – 35 mmol —Bicarbonate – 20 mmol —Potassium – 10 mmol