inositol nicotinate
CLINICAL USE
Peripheral vascular disease
DOSE IN NORMAL RENAL FUNCTION
3 g daily in 2–3 divided doses, maximum 4 g daily
PHARMACOKINETICS
DOSE IN RENAL IMPAIRMENT
GFR (mL/MIN)
30–50 Dose as in normal renal function10–30 Dose as in normal renal function
DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES
IMPORTANT DRUG INTERACTIONS
Potentially hazardous interactions with other drugs
ADMINISTRATION
Reconstition
–
Route
Oral
Rate of Administration
–
Comments
–
OTHER INFORMATION
Slowly hydrolysed to nicotinic acid inositol nicotinate.