Flutamide
CLINICAL USE
Treatment of advanced prostate cancer
DOSE IN NORMAL RENAL FUNCTION
250 mg every 8 hours; start 3 days before LHRH agonist
PHARMACOKINETICS
DOSE IN RENAL IMPAIRMENT
GFR (mL/MIN)
DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES
IMPORTANT DRUG INTERACTIONS
Potentially hazardous interactions with other drugs
ADMINISTRATION
Reconstition
–
Route
Oral
Rate of Administration
–