Aciclovir oral
CLINICAL USE
Antiviral agent:
DOSE IN NORMAL RENAL FUNCTION
PHARMACOKINETICS
DOSE IN RENAL IMPAIRMENT
GFR (mL/MIN)
25–50 Dose as in normal renal function 10–25 Simplex: 200 mg 3–4 times daily. Zoster: 800 mg every 8–12 hours
DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES
IMPORTANT DRUG INTERACTIONS
Potentially hazardous interactions with other drugs
ADMINISTRATION
Reconstition
–
Route
Oral
Rate of Administration
–
Comments
Dispersible tablets may be dispersed in a minimum of 50 mL of water or swallowed whole with a little water