{"id":981,"date":"2023-01-13T11:21:33","date_gmt":"2023-01-13T11:21:33","guid":{"rendered":"https:\/\/kidneydiseaseclinic.net\/blog\/?p=981"},"modified":"2023-01-13T11:22:27","modified_gmt":"2023-01-13T11:22:27","slug":"description","status":"publish","type":"post","link":"https:\/\/kidneydiseaseclinic.net\/blog\/description\/","title":{"rendered":"Allopurinol 100 MG"},"content":{"rendered":"\n<p><\/p>\n\n\n\n<p>A xanthine oxidase inhibitor that decreases uric acid production. It also acts as an antimetabolite on some simpler organisms.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">CATEGORIES<\/h2>\n\n\n\n<p>Gout Suppressants,Enzyme Inhibitors,Antimetabolites,Free Radical Scavengers .<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">CHEMICAL FORMULA<\/h2>\n\n\n\n<p>C5H4N4O<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">COMPOSITION<\/h2>\n\n\n\n<p>Allopurinol 100 MG<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">INDICATION<\/h2>\n\n\n\n<p>For the treatment of hyperuricemia associated with primary or secondary gout. Also indicated for the treatment of primary or secondary uric acid nephropathy, with or without the symptoms of gout, as well as chemotherapy-induced hyperuricemia and recurrent renal calculi.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">PHARMACODYNAMICS<\/h2>\n\n\n\n<p>Allopurinol, a structural analog of the natural purine base hypoxanthine, is used to prevent gout and renal calculi due to either uric acid or calcium oxalate and to treat uric acid nephropathy, hyperuricemia, and some solid tumors.<\/p>\n\n\n\n<p>No Information<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">ABSORPTION<\/h2>\n\n\n\n<p>Approximately 80-90% absorbed from the gastrointestinal tract.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">METABOLISM<\/h2>\n\n\n\n<p>Hepatic<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">ELIMINATION<\/h2>\n\n\n\n<p>Approximately 20% of the ingested allopurinol is excreted in the feces.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">HALF LIFE<\/h2>\n\n\n\n<p>1-3 hours<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">TOXICITY<\/h2>\n\n\n\n<p>LD50=214 mg\/kg (in mice)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">FOOD INTERACTIONS<\/h2>\n\n\n\n<p>avoid alcohol<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">SIDE EFFECTS<\/h2>\n\n\n\n<p>Skin irritation. Upset stomach or throwing up.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A xanthine oxidase inhibitor that decreases uric acid production. It also acts as an antimetabolite on some simpler organisms. CATEGORIES Gout Suppressants,Enzyme Inhibitors,Antimetabolites,Free Radical Scavengers . CHEMICAL FORMULA C5H4N4O COMPOSITION Allopurinol 100 MG INDICATION For the treatment of hyperuricemia associated with primary or secondary gout. Also indicated for the treatment of primary or secondary uric [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-981","post","type-post","status-publish","format-standard","hentry","category-med"],"_links":{"self":[{"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/posts\/981","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/comments?post=981"}],"version-history":[{"count":2,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/posts\/981\/revisions"}],"predecessor-version":[{"id":983,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/posts\/981\/revisions\/983"}],"wp:attachment":[{"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/media?parent=981"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/categories?post=981"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/tags?post=981"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}