{"id":1113,"date":"2023-01-13T15:59:22","date_gmt":"2023-01-13T15:59:22","guid":{"rendered":"https:\/\/kidneydiseaseclinic.net\/blog\/?p=1113"},"modified":"2023-01-13T15:59:22","modified_gmt":"2023-01-13T15:59:22","slug":"xylometazoline","status":"publish","type":"post","link":"https:\/\/kidneydiseaseclinic.net\/blog\/xylometazoline\/","title":{"rendered":"Xylometazoline"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">DESCRIPTION<\/h2>\n\n\n\n<p>A nasal vasoconstricting decongestant drug which acts by binding to the same receptors as adrenaline. It is applied as a spray or as drops into the nose to ease inflammation and congestion of the nasal passageways. It binds alpha-adrenergic receptors to activate the adrenal system which causes systemic vasoconstriction, thereby easing nasal congestion.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">CHEMICAL FORMULA<\/h2>\n\n\n\n<p>C16H24N2<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">COMPOSITION<\/h2>\n\n\n\n<p>Xylometazoline Hydrochloride 0.1 %W\/V<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">INDICATION<\/h2>\n\n\n\n<p>It is used for treating nasal congestion and minor inflammation due to allergies or colds.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">PHARMACODYNAMICS<\/h2>\n\n\n\n<p>Xylometazoline is a direct acting sympathomimetic adrenergic alpha-agonist used to induce systemic vasoconstriction, thereby decreasing nasal congestion. The sympathomimetic action of xylometazoline constricts the smaller arterioles of the nasal passages, producing a prolonged (8-12 hours) decongesting effect.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">MECHANISM<\/h2>\n\n\n\n<p>Xylometazoline is a direct acting sympathomimetic drug, which acts on alpha-adrenergic receptors in the arterioles of the nasal mucosa. This activates the adrenal system to yield systemic vasoconstrction. In producing vasoconstriction, the result is a decrease in blood flow in the nasal passages and consequently decreased nasal congestion.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>DESCRIPTION A nasal vasoconstricting decongestant drug which acts by binding to the same receptors as adrenaline. It is applied as a spray or as drops into the nose to ease inflammation and congestion of the nasal passageways. It binds alpha-adrenergic receptors to activate the adrenal system which causes systemic vasoconstriction, thereby easing nasal congestion. CHEMICAL [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1113","post","type-post","status-publish","format-standard","hentry","category-med"],"_links":{"self":[{"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/posts\/1113","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/comments?post=1113"}],"version-history":[{"count":1,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/posts\/1113\/revisions"}],"predecessor-version":[{"id":1114,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/posts\/1113\/revisions\/1114"}],"wp:attachment":[{"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/media?parent=1113"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/categories?post=1113"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/tags?post=1113"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}