{"id":1004,"date":"2023-01-13T11:29:58","date_gmt":"2023-01-13T11:29:58","guid":{"rendered":"https:\/\/kidneydiseaseclinic.net\/blog\/?p=1004"},"modified":"2023-01-13T11:29:58","modified_gmt":"2023-01-13T11:29:58","slug":"bisacodyl-5-mg","status":"publish","type":"post","link":"https:\/\/kidneydiseaseclinic.net\/blog\/bisacodyl-5-mg\/","title":{"rendered":"Bisacodyl 5 mg"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">DESCRIPTION<\/h2>\n\n\n\n<p>Bisacodyl is an organic compound that is used as a stimulant laxative drug. It works directly on the colon to produce a bowel movement. It is typically prescribed for relief of constipation and for the management of neurogenic bowel dysfunction as well as part of bowel preparation before medical examinations, such as for a colonoscopy.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">CATEGORIES<\/h2>\n\n\n\n<p>Laxatives, Purgatives .<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">CHEMICAL FORMULA<\/h2>\n\n\n\n<p>C22H19NO4<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">COMPOSITION<\/h2>\n\n\n\n<p>Bisacodyl 5 mg<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">INDICATION<\/h2>\n\n\n\n<p>Indicated for cleansing of the colon as a preparation for colonoscopy in adults.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">PHARMACODYNAMICS<\/h2>\n\n\n\n<p>Bisacodyl is hydrolyzed by intestinal brush border enzymes and colonic bacteria to form an active metabolite [bis-(p-hydroxyphenyl) pyridyl-2 methane; (BHPM)] that acts directly on the colonic mucosa to produce colonic peristalsis.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">MECHANISM<\/h2>\n\n\n\n<p>Induces diarrhea which cleanses the colon.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">ABSORPTION<\/h2>\n\n\n\n<p>15%<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">METABOLISM<\/h2>\n\n\n\n<p>Hepatic (CYP450-mediated).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">ELIMINATION<\/h2>\n\n\n\n<p>primarily in the feces, systemically absorbed drug is excreted in the urine<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">HALF LIFE<\/h2>\n\n\n\n<p>16 hours<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">FOOD INTERACTIONS<\/h2>\n\n\n\n<p>avoid alcohol<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">SIDE EFFECTS<\/h2>\n\n\n\n<p>Mild cramps, nausea, diarrhea, abdominal discomfort, stomach and intestinal irritation, faintness, irritation or burning in the rectum (from suppositories and enemas).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>DESCRIPTION Bisacodyl is an organic compound that is used as a stimulant laxative drug. It works directly on the colon to produce a bowel movement. It is typically prescribed for relief of constipation and for the management of neurogenic bowel dysfunction as well as part of bowel preparation before medical examinations, such as for a [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1004","post","type-post","status-publish","format-standard","hentry","category-med"],"_links":{"self":[{"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/posts\/1004","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/comments?post=1004"}],"version-history":[{"count":1,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/posts\/1004\/revisions"}],"predecessor-version":[{"id":1005,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/posts\/1004\/revisions\/1005"}],"wp:attachment":[{"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/media?parent=1004"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/categories?post=1004"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kidneydiseaseclinic.net\/blog\/wp-json\/wp\/v2\/tags?post=1004"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}